Replacement PTFE Diaphragms for Shimadzu® LC Pumps

Keeping an HPLC system running is often a parts problem, not a technology problem.

The pump diaphragms wear out, and suddenly you encounter pressure drift, leakage, or unstable baselines. This technical note introduces our two compatible PTFE diaphragm sets that replace common Shimadzu® OEM part numbers:

• 228-55272-41 – For LC-30AD / i-Series
• 228-32784-91 – For LC-10/20/2010 / LC-30ADSF family (replaces old numbers 228-24311-01, 228-31828-00, Sciex™ 4425151)

Quick Overview

OEM numbers are for identification only. Products are manufactured by XHH Seals, not by Shimadzu® or Sciex™.

Replacement for 228-55272-41 – LC-30AD / i-Series

This PTFE diaphragm is designed as a drop-in compatible part for Shimadzu® LC-30AD and i-Series pumps.

Key features:

• Direct Alternative: Matches the dimensions and function of OEM 228-55272-41.
• Service Ready: 2 pieces per pack – sufficient for one complete pump head service.
• Chemical Resistance: Manufactured from high-purity PTFE to resist common mobile phases, buffers, and cleaning solvents.
• Performance: Molded sealing edge designed to maintain vacuum integrity and pressure stability at typical LC-30AD operating pressures.

Typical use cases:

• Routine preventive maintenance (PM) of LC-30AD / i-Series systems.
• Resolving pressure fluctuations or leakage caused by worn diaphragms.
• Reducing service costs without replacing the entire pump hardware.

If your service report or purchase history lists 228-55272-41, this is the exact replacement you need.

Replacement for 228-32784-91 – LC-10/20/2010 & LC-30ADSF

The second product targets older and mid-generation Shimadzu® pumps. It is a PTFE diaphragm set compatible with OEM 228-32784-91, and serves as a replacement for several legacy numbers: 228-24311-01, 228-31828-00, and Sciex™ 4425151.

Compatible pump models:

• LC-10AD / LC-10ADvp
• LC-2010 / LC-2010HT
• LC-20AD / LC-20AB / LC-20ADXR
• LC-30ADSF
• Selected LC-20 rinse / auxiliary pumps using part number 4425151.

Important Technical Note: Incompatibility Warning: Please note that 228-32784-91 is NOT compatible with LC-30AD or i-Series main pumps. If your lab operates both legacy LC-10/20 systems and newer LC-30AD systems, you will need to stock both diaphragm types to cover your installed base.

Key features:

• Pack Size: 1 pack contains 2 PTFE diaphragms.
• Function: Direct functional replacement for OEM and legacy part numbers.
• Durability: PTFE construction handles standard HPLC mobile phases and aggressive cleaning cycles.
• Restoration: Helps restore flow accuracy and gradient reproducibility on aging pumps.

How to Order, Check Compatibility & Custom Solutions

We make procurement simple and flexible. Depending on your needs, please choose one of the following options when sending an inquiry:

Option A: For Standard Shimadzu® Replacements To ensure you get the exact match for your pump, please share:

• Your Pump Model: (e.g., LC-30AD, LC-10ADvp, LC-20ADXR)
• The OEM Part Number: Found on your service report or packaging (228-55272-41, 228-32784-91, etc.)
• Quantity: The number of packs required.

Option B: Custom Manufacturing Services (OEM/ODM) If you require a seal that is not listed, or need parts for an obsolete pump model, XHH Seals offers full customization capabilities.

• Send us your Technical Drawings: We accept PDF, CAD, or 3D files.
• Provide Samples: If drawings are unavailable, we can reverse-engineer from new or used samples.
• Material Selection: We can customize dimensions using our high-performance PTFE, UHMWPE, or PEEK materials.

Next Steps: We will review your request—whether it's a standard cross-reference or a custom engineering project—and send you a formal quotation within 24 hours.

[Email Us xhh@xhh-smartech.com]

Besides diaphragms, XHH Seals manufactures a wide variety of high-performance HPLC seals compatible with major instrument brands.

Disclaimer: Shimadzu® and Sciex™ are registered trademarks of their respective owners. All OEM numbers (228-55272-41, 228-32784-91, 228-24311-01, 228-31828-00, 4425151, etc.) are used for identification and cross-reference purposes only. XHH Seals is an independent manufacturer and is not affiliated with, authorized by, or endorsed by these companies.