Waters HPLC Seals: Compatible Replacement Parts & Cost-Saving Alternatives

High-performance liquid chromatography (HPLC) systems from Waters®—including Alliance®, ACQUITY® UPLC, and classic 2690/2695 series—rely on precision seals to ensure reliable performance. Over time, pump seals, injector seals, and wash seals wear down, causing leaks, unstable pressure, and costly downtime.

Switching to compatible Waters HPLC seals gives labs a cost-effective solution. These aftermarket Waters seals are engineered with high-quality materials like UHMWPE, PTFE, and stainless steel springs, delivering OEM-equivalent performance at 30–60% lower cost.

Why Choose Compatible Waters HPLC Seals?

• Direct OEM Replacement: All seals are designed to match original dimensions (e.g., injector seal WAT033276, plunger seal kits WAT270938, wash tube seals WAT270940/WAT270668).
• Wide Compatibility: Suitable for Waters 2690, 2695, 2790, 2795, 2796, 510, 515, 600, Alliance® and ACQUITY® UPLC systems.
• Material Quality: Made from UHMWPE, PTFE, PEEK™, Elgiloy, or 316 stainless steel for long-lasting durability.
• Lower Maintenance Costs: Labs typically save thousands annually by using aftermarket Waters HPLC seal replacements.

Popular Compatible Waters Seal Replacements

1. Pump & Plunger Seals

Head Plunger Seal Kits (WAT271066, WAT270938): Designed for Waters Alliance® and 2690/2695 pumps.

Black Plunger Seal (WAT026613): OEM-equivalent for 510, 515, and 1525 systems.

Classic Plunger Seal (WAT022934): Widely used across Waters 510/515/600 series.

2. Injector & Face Seals

Injector Seal WAT033276: Compatible with Waters Alliance systems, ensuring reliable sample introduction.

Face Seal Kit (WAT270939): 4-pack set for Waters 2690, 2695, and 2790 series.

3. Wash Seals & Seal Kits

Wash Seal WAT045454: Gold seals for 2690/2695 Alliance® HPLC.

Wash Tube Seal Kit (WAT270940/WAT270668): Designed for Waters 2790, 2795, and Alliance systems.

Wash Plunger Seal (WAT271018/WAT270160): Provides excellent solvent flow and system protection.

Wash Seal Compatible with ACQUITY® (425000307/ 700002598 & 700002599): Ideal for UPLC and nanoACQUITY® BSM/ASM units.

4. Oil Seals

Oil Seal WAT025669/ WAT005081: Reliable replacement for Waters 510, 515, 600, and 1525 pumps.

OEM vs Compatible Waters HPLC Seals

Many labs have already transitioned to compatible Waters seals and reported significant savings without compromising reliability.

Frequently Asked Questions

Q: Can I use compatible seals for Waters ACQUITY® UPLC systems?

A: Yes, we supply Waters ACQUITY UPLC seals (e.g., injector and wash seals, P/N 700002598, 700002599).

Q: How long do aftermarket Waters seals last compared to OEM?

A: With proper maintenance, compatible seals provide 6–12 months of service life, equivalent to OEM parts.

Get a Quote Today

Whether you need Waters injector seals, pump plunger seals, or wash seal kits, our compatible replacements offer the same performance as OEM parts—at a fraction of the cost. xhh@xhh-smartech.com

Disclaimer:

These are compatible replacement parts, not manufactured or endorsed by Waters®. All trademarks are property of their respective owners.

Agilent HPLC Seal Replacement Guide