Compatible HPLC Seals

Looking for reliable replacement seals for your HPLC systems? We offer a full range of compatible HPLC pump seals designed to fit leading brands like Agilent, Waters, Shimadzu, and more. Our seals deliver high chemical resistance, precise fitment, and long service life—ideal for laboratories, instrument service providers, and OEM partners.

Out-of-Stock
Compatible Piston Seal for Agilent 1050/1100/1200/1260 (P/N 5063-6589)
This high-performance piston seal is designed as a drop-in replacement for Agilent P/N 5063-6589, compatible with a wide range of Agilent HPLC pump systems, including 1050, 1100, 1120, 1200, 1220, 1260 Infinity, and various pump modules (G1310A/B, G1311A/B/C, G1312A/B/C, G2226A, G4302A).
The seal features a carbon-filled PTFE sealing element reinforced with a 316 stainless steel spring, delivering excellent chemical resistance, low wear, and consistent sealing under high-pressure gradient conditions.
Out-of-Stock
Piston Seals Compatible with Agilent 1090 – Replaces 5062-2494
This high-quality piston seal is a direct replacement for Agilent part number 5062-2494, designed to deliver reliable performance in Agilent 1090 HPLC pumps. Manufactured using virgin PTFE (Teflon) and reinforced with a 316 stainless steel spring, this seal ensures long-term durability, superior chemical resistance, and leak-proof operation under high-pressure HPLC conditions.
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Injector Seal Compatible with Waters HPLC – Replaces WAT033276
This high-precision injector seal is a compatible replacement for Waters OEM part numbers WAT033276 and 700002760. It is used in the autosampler module of Waters HPLC systems, including 2690, 2695, 2690D, and 2695D.
Crafted from durable UHMWPE (Ultra High Molecular Weight Polyethylene) and corrosion-resistant 316 stainless steel, this seal ensures robust sealing performance, excellent chemical resistance, and minimal sample carryover.
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Wash Seal Compatible with Waters HPLC – Replaces 425000307 / 700002598
This high-precision wash seal is a compatible replacement for Waters OEM P/N 425000307 and 700002598, designed to support a wide range of Waters HPLC systems. Suitable for Waters Acquity, H-Class, Alliance, and nanoAcquity platforms, it offers excellent sealing performance under standard to high-pressure HPLC conditions.
Manufactured from UHMWPE (ultra-high molecular weight polyethylene) with a 316 stainless steel support ring, this seal offers excellent chemical resistance, dimensional stability, and wear durability—making it ideal for high-throughput labs running sensitive analyses.
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Wash Seal Compatible with Waters HPLC – Replaces 700002599
This high-performance wash seal is a compatible replacement for Waters OEM P/N 700002599. Designed for use in Waters ACQUITY and nanoACQUITY UHPLC systems, it delivers long-lasting durability, leak resistance, and stable flow performance.
Crafted from UHMWPE, 316 stainless steel, and PEEK™, this seal provides robust chemical resistance and mechanical integrity—ideal for high-throughput analytical workflows.
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HPMV Gold Seal Compatible with Waters HPLC – Replaces WAT045454
This HPMV Gold Seal is a high-precision, compatible replacement for Waters OEM part number WAT045454. Specifically designed for critical injection and flow control components, it helps maintain leak-free, stable operation in Waters Alliance HPLC systems.
Manufactured from UHMWPE (Ultra High Molecular Weight Polyethylene) and Elgiloy®, this aftermarket seal provides long-lasting chemical resistance, pressure stability, and flexibility for high-throughput labs.
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Wash Tube Seal Kit Compatible with Waters HPLC – Replaces WAT270940 / WAT270668
This Wash Tube Seal Kit is a compatible replacement for Waters OEM part numbers WAT270940 and WAT270668, designed for use in a variety of Waters Alliance HPLC systems.
Featuring UHMWPE sealing surfaces and a corrosion-resistant stainless steel spring, this kit helps maintain solvent flushing efficiency and protects your injector components from contamination buildup. Ideal for routine service or preventive maintenance.
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Wash Plunger Seal Compatible with Waters HPLC – Replaces WAT271018 / WAT270160
This Wash Plunger Seal is a high-quality compatible replacement for Waters® OEM part numbers WAT271018 and WAT270160, designed to maintain optimal sealing and solvent flushing in Waters Alliance series HPLC systems.
Constructed from UHMWPE with a corrosion-resistant 316 stainless steel spring, this seal helps prevent carryover, prolongs injector life, and supports stable pump performance.