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HPLC seals are critical components that ensure leak-free performance, pressure stability, and chemical compatibility in liquid chromatography systems. Whether you're replacing worn piston seals, valve isolation seals, or wash seals, using high-quality components is essential for accurate and repeatable results.

Our HPLC seals are compatible with major OEM brands, including Agilent, Waters, Shimadzu, and Thermo Scientific.

  • Agilent HPLC Seal Replacement Guide: Compatible, Cost-Effective Alternatives
    Agilent HPLC Seal Replacement Guide: Compatible, Cost-Effective Alternatives
    951 Views

    High-performance liquid chromatography (HPLC) systems, like those from Agilent, rely on precision seals to maintain fluid integrity and analytical accuracy. Over time, these seals degrade, increasing the risk of leaks, pressure instability, or sample contamination. Replacing worn components with compatible, cost-effective alternatives can save your lab money—without sacrificing performance.       In this guide, we explore the most common Agilent HPLC seal models, provide high-quality...

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  • Waters HPLC Seals: Compatible Replacement Parts & Cost-Saving Alternatives
    Waters HPLC Seals: Compatible Replacement Parts & Cost-Saving Alternatives
    714 Views

    High-performance liquid chromatography (HPLC) systems from Waters®—including Alliance®, ACQUITY® UPLC, and classic 2690/2695 series—rely on precision seals to ensure reliable performance. Over time, pump seals, injector seals, and wash seals wear down, causing leaks, unstable pressure, and costly downtime. Switching to compatible Waters HPLC seals gives labs a cost-effective solution. These aftermarket Waters seals are engineered with high-quality materials like UHMWPE, PTFE, and stainless...

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  • Replacement PTFE Diaphragms for Shimadzu® LC Pumps
    Replacement PTFE Diaphragms for Shimadzu® LC Pumps
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    Keeping an HPLC system running is often a parts problem, not a technology problem. The pump diaphragms wear out, and suddenly you encounter pressure drift, leakage, or unstable baselines. This technical note introduces our two compatible PTFE diaphragm sets that replace common Shimadzu® OEM part numbers:228-55272-41 – For LC-30AD / i-Series 228-32784-91 – For LC-10/20/2010 / LC-30ADSF family (replaces old numbers 228-24311-01, 228-31828-00, Sciex™ 4425151)Quick OverviewOur Product...

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